 |
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|---|---|---|
| 【ProductName】 |
AMOTL2 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K114400P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9Y2J4 |
|
| 【Gene ID】 |
51421 |
|
| 【Application】 |
Blocking Peptide of K114400P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
Regulates the translocation of phosphorylated SRC to peripheral cell-matrix adhesion sites. Required for proper architecture of actin filaments. Inhibits the Wnt/beta-catenin signaling pathway， probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus. Participates in angiogenesis. May play a role in the polarity， proliferation and migration of endothelial cells. Selectively promotes FGF-induced MAPK activation through SRC.