 |
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|---|---|---|
| 【ProductName】 |
RANGRF Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K113151P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9HD47 |
|
| 【Gene ID】 |
29098 |
|
| 【Application】 |
Blocking Peptide of K113151P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
May regulate the intracellular trafficking of RAN (PubMed:11290418).Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1 (PubMed:29040603).Regulates the levels of GTP-bound RAN in the nucleus， and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (PubMed:29040603).Enhances the expression of SCN5A at the cell membrane in cardiomyocytes (PubMed:18184654， PubMed:23420830， PubMed:21621375).