 |
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|---|---|---|
| 【ProductName】 |
POLE Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K113101P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q07864 |
|
| 【Gene ID】 |
5426 |
|
| 【Application】 |
Blocking Peptide of K113101P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Catalytic component of the DNA polymerase epsilon complex (PubMed:10801849).Participates in chromosomal DNA replication (By similarity).Required during synthesis of the leading DNA strands at the replication fork， binds at/or near replication origins and moves along DNA with the replication fork (By similarity).Has 3’-5’ proofreading exonuclease activity that corrects errors arising during DNA replication (By similarity).Involved in DNA synthesis during DNA repair (PubMed:20227374， PubMed:27573199).Along with DNA polymerase POLD1 and DNA polymerase POLK， has a role in excision repair (NER) synthesis following UV irradiation (PubMed:20227374).