 |
||
|---|---|---|
| 【ProductName】 |
SHLD2 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K111141P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q86V20 |
|
| 【Gene ID】 |
54537 |
|
| 【Application】 |
Blocking Peptide of K111141P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
Component of the shieldin complex， which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893， PubMed:29789392). During G1 and S phase of the cell cycle， the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893， PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination， and fusion of unprotected telomeres (PubMed:29656893).