 |
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|---|---|---|
| 【ProductName】 |
MYSM1 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107504P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q5VVJ2 |
|
| 【Gene ID】 |
114803 |
|
| 【Application】 |
Blocking Peptide of K107504P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A， a specific tag for epigenetic transcriptional repression， thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation. Required for correct regulation of hematopoiesis and lymphocyte differentiation (PubMed:28115216， PubMed:26220525).