 |
||
|---|---|---|
| 【ProductName】 |
TNFRSF10B Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K107153P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
O14763 |
|
| 【Gene ID】 |
8795 |
|
| 【Application】 |
Blocking Peptide of K107153P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
|
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Background：
The protein encoded by this gene is a member of the TNF-receptor superfamily， and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L)， and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD， a death domain containing adaptor protein， is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene.