 |
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|---|---|---|
| 【ProductName】 |
ITGAL Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K106784P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P20701 |
|
| 【Gene ID】 |
3683 |
|
| 【Application】 |
Blocking Peptide of K106784P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
|
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Background：
ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1)， which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands， ICAMs 1-3 (intercellular adhesion molecules 1 through 3)， and also functions in lymphocyte costimulatory signaling.