Product Specification
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|---|---|---|
| 【ProductName】 |
IRAK4 Antibody Blocking Peptide |
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| 【Cat NO.】 |
K106734P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
Q9NWZ3 |
|
| 【Gene ID】 |
51135 |
|
| 【Application】 |
Blocking Peptide of K106734P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
Serine/threonine-protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll-like receptor (TLR) and IL-1R signaling pathways. Is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation to form the Myddosome together with IRAK2. Phosphorylates initially IRAK1， thus stimulating the kinase activity and intensive autophosphorylation of IRAK1.