 |
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|---|---|---|
| 【ProductName】 |
IL12 Antibody Blocking Peptide |
|
| 【Cat NO.】 |
K106473P-Ag |
|
| 【Source】 |
Synthetic |
|
| 【Storage】 |
Store at -20℃，2 years.Avoid freeze/thaw cycles. |
|
| 【Appearance】 |
Lyophilized powder |
|
| 【Swiss Prot】 |
P29459 |
|
| 【Gene ID】 |
3592 |
|
| 【Application】 |
Blocking Peptide of K106473P Antibody |
|
| 【Purification】 |
HPLC |
|
| 【Activity】 |
Not tested |
|
| 【Note】 |
Please allow the product to equilibrate to room temperature in a dry environment before opening the packaging. |
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Background：
IL-12 protein is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines， MHC class II Ags， and costimulatory molecules on macrophages. It also enhances B cell survival， proliferation， and antibody production. This cytokine can block NF-kappa B activity， and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.